Basic Fluvoxamine Information

• INN (International Nonproprietary Name): Fluvoxamine
• Brand Names Available in Australia: Luvox, Fevarin
• ATC Code: N06AB08
• Forms & Dosages: Tablets (50 mg, 100 mg)
• Manufacturers in Australia: Aspen Pharma, generic companies
• Registration Status in Australia: Prescription only
• OTC / Rx Classification: Rx only

High-Risk Groups

Fluvoxamine has specific safety warnings for certain demographics. Elderly patients may experience heightened sensitivity and adverse effects. For this reason, special caution is necessary when prescribing fluvoxamine to this group.

Pregnant individuals should always consult their healthcare provider as fluvoxamine may affect fetal development. The importance of discussing medication use during pregnancy cannot be overstated, as it is essential for both the mother and child's health.

Chronic illnesses, particularly liver diseases, require cautious dosage adjustments to avoid complications. Those with existing health issues should communicate openly with their healthcare providers to establish a suitable treatment plan.

Interaction With Activities

When it comes to engaging in potentially hazardous activities, patients are advised against driving or operating heavy machinery until they fully understand how fluvoxamine affects them. Different individuals may react differently to medications, and safety must be the priority.

The Australian law mandates that employers ensure workplace safety, which extends to employees on antidepressants. It's crucial for both employees and employers to be aware of how medications can influence work performance and safety.

Q&A — “Can I Drive After Taking It In Australia?”

Q: Can I drive after taking fluvoxamine?
A: It is advisable to refrain from driving until you know how fluvoxamine affects your concentration and reflexes. Seek guidance from your healthcare provider. This recommendation is essential to ensure that both the driver and others on the road are safe.

Having open discussions with healthcare professionals can provide necessary insights and ensure proper management of any potential side effects that may arise while taking fluvoxamine. The goal is to balance the effective treatment of mental health conditions without compromising safety in everyday activities.

Mechanism & Pharmacology

Fluvoxamine operates as a selective serotonin reuptake inhibitor (SSRI), primarily increasing serotonin levels in the brain, which can enhance mood and reduce anxiety. By blocking the reuptake of serotonin, fluvoxamine aims to restore balance in neurotransmitter activity, notably beneficial for individuals with OCD and other anxiety-related conditions.

In clinical terms, fluvoxamine is identified under the ATC code N06AB08. Its pharmacodynamics reflects its role in modulating serotonin signals, contributing to enhanced emotional regulation and decreased compulsive behaviours in patients.

Indications & Off-Label Uses

The Therapeutic Goods Administration (TGA) approves fluvoxamine primarily for the treatment of obsessive-compulsive disorder (OCD). It's also prescribed for depression and anxiety disorders, highlighting its versatility in mental health treatment within Australian clinical practice.

Beyond its approved uses, fluvoxamine is sometimes prescribed off-label for conditions such as post-traumatic stress disorder (PTSD) and social anxiety disorder. Healthcare providers may consider these off-label uses based on individual patient needs and clinical guidelines.

Key Clinical Findings

Significant studies conducted within Australia and globally from 2022 to 2025 have focused on fluvoxamine's efficacy in treating various mental health conditions. Results have consistently demonstrated that fluvoxamine effectively reduces OCD symptoms. Comparative studies against other SSRIs have indicated its distinct profile, making it a valuable option in the therapeutic landscape.

Moreover, recent clinical trials suggest promising outcomes for fluvoxamine in treating severe anxiety disorders. These findings advocate for fluvoxamine's inclusion in treatment guidelines and clinical pathways to ensure optimal patient care and outcomes.

Alternatives Matrix

Pros: Effective for various anxiety disorders, well-studied.

Cons: Side effects may include sexual dysfunction and weight gain.

Common Questions

Many patients using fluvoxamine may have common queries regarding its usage. This includes questions surrounding the duration of treatment, potential side effects, and strategies for managing missed doses. Pharmacists play a critical role in providing reassurance, clarifying uncertainties, and emphasising adherence to prescribed regimens for optimal results.

Suggested Visual Content

Infographics and visual aids can enhance patient understanding of fluvoxamine's benefits and risks. Easily digestible information assists in navigating treatment options.

• PBS pricing chart: A clear depiction of fluvoxamine's cost compared to its alternatives, providing a quick reference point for patients.
• Pharmacy network map: Highlighting locations where fluvoxamine is available, including major chains like Chemist Warehouse and Priceline, ensures that patients know where to go for their medications.

These resources empower patients to make informed decisions about their treatment plans.

Registration & Regulation

TGA approval

Fluvoxamine has received formal approval from the TGA in Australia. This approval ensures that the medication is safe and effective for consumers. The TGA conducts regular reviews and updates, evaluating new data to maintain high safety standards.

PBS subsidy details

The PBS subsidy enables Australians to access fluvoxamine at a lower cost, easing the financial burden for those needing treatment. To benefit from this subsidy, patients must meet specific eligibility criteria, requiring a prescription from a healthcare practitioner.

Storage & Handling

Household storage in Australian climate

For optimal stability, fluvoxamine should be stored in a cool, dry place away from excessive heat and humidity often experienced in various Australian climates. A temperature range of 15°C to 30°C is ideal.

Cold-chain handling for pharmacies

Pharmacies must adhere to strict protocols to ensure the safe storage and handling of fluvoxamine. Although it doesn’t require cold-chain conditions, continuous monitoring of storage environments is critical to maintain product integrity.

Guidelines for Proper Use

Australian pharmacist counselling style

Pharmacists in Australia are encouraged to engage patients effectively, offering clear instructions on fluvoxamine usage, including expected benefits and potential side effects. They should also discuss interactions with other medications openly.

Patient advice from PBS and national health authorities

Patients should be well-informed about adhering to prescribed dosages and durations. It’s beneficial for them to have regular consultations with healthcare professionals and pharmacists, facilitating the optimisation of treatment plans and adjustments driven by side effects or emerging health concerns.

Delivery Information for Fluvoxamine